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 Aciphex

Aciphex is a proton pump inhibitor used to treat ulcers, gastroesophageal reflux disease, erosive esophagitis, or Zollinger-Ellison syndrome. Aciphex works by blocking acid production in the stomach. Aciphex may be used in combination with antibiotics including amoxicillin or clarithromycin to treat certain types of ulcers. Aciphex may also be used to treat other conditions as determined by your doctor.



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ACIPHEX DRUG INFO

ACTIVE INGREDIENT:

RABEPRAZOLE (ra-BE-pray-zole) - ORAL


COMMON BRAND NAME(S):

Aciphex


USES:

This medicine is a proton pump inhibitor (PPI) used to treat ulcers, gastroesophageal reflux disease (GERD), erosive esophagitis, or Zollinger-Ellison syndrome. This medicine works by blocking acid production in the stomach. It may be used in combination with antibiotics including amoxicillin or clarithromycin to treat certain types of ulcers. It may also be used to treat other conditions as determined by your doctor.


HOW TO USE:

Rabeprazole comes as a delayed-release (long-acting) tablet to take by mouth. It is usually taken once a day for 4 to 8 weeks, but it is sometimes taken for a longer time. When taken for ulcers, rabeprazole should be taken after the morning meal. Swallow the tablets whole; do not split, chew, or crush them.


SIDE EFFECTS:

Rabeprazole may cause side effects. Tell your doctor if these symptoms are severe or do not go away:

  • headache
  • upset stomach
  • diarrhea
  • stomach pain
  • vomiting
  • constipation
  • dry mouth
  • increased or decreased appetite
  • muscle or bone pain
  • drowsiness
  • dizziness
  • difficulty falling asleep or staying asleep

There may be other side effects from rabeprazole. Call your doctor if you have any unusual problems while taking this medication.


PRECAUTIONS:

Before taking rabeprazole,

  • tell your doctor and pharmacist if you are allergic to rabeprazole, lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), or any other medications.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: cyclosporine (Neoral, Sandimmune), digoxin (Lanoxin), and ketoconazole (Nizoral). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had liver disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking rabeprazole, call your doctor.

DRUG INTERACTIONS:

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking rabeprazole, it is especially important that your health care professional know if you are taking any of the following: cyclosporine (e.g., Neoral)—Rabeprazole may increase the amount of cyclosporine in the blood, digoxin (e.g., Lanoxin)—Rabeprazole may increase the amount of digoxin in the blood, ketoconazole (e.g., Nizoral tablets)—Rabeprazole may decrease the amount of ketoconazole absorbed into the body, warfarin (e.g., Coumadin)—May cause serious unwanted effects including abnormal bleeding.


OVERDOSE:

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.


NOTES:

Keep all appointments with your doctor and the laboratory. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.


MISSED DOSE:

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.


STORAGE:

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.



IMPORTANT NOTE:

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

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